Georgia Bio Names South Forsyth High School Junior as 2022 Georgia BioGENEius Winner

Mokshith Mannuru Advances to International Competition Against Top Students

Georgia Bio and the BioEd Institute named  Mokshith Mannuru , a junior at South Forsyth High School in Cumming, GA, as the winner of the 2022 Georgia BioGENEius Challenge. The BioGENEius Challenge is the premier competition for high school students that recognizes outstanding research and innovation in the biotechnology field. As Georgia’s BioGENEius finalist, Mokshith will attend the 2022 International BioGENEius competition, which will be held during the 2022 BIO International Convention, the industry’s trade conference from June 13-16 in San Diego, CA. There he will engage with leading companies, scientists and innovators currently transforming the scientific landscape and gain valuable insights into an industry making significant contributions to the world.

While in San Diego, Mokshith will compete against high school students from the U.S., Canada, and Germany in the International BioGENEius Challenge. The student projects will represent a range of biotechnology topics such as healthcare, agriculture, and the environment.

Mokshith’s project uses bioinformatics to identify the common function of genes that are related to Autism Spectrum Disorder (ASD). Over 1,000 genes are evidenced to contribute to ASD but are not understood well enough to use genetics in diagnosing or treating ASD. Mokshith hypothesized that these genes contribute to human development and would therefore affect development if a copy of the gene were faulty. He used data from the International Mouse Phenotyping Consortium (IMPC) to observe the phenotypes of mice where the ASD genes that are also found in mice were knocked out (deleted). The missing genes were found to strongly affect development or behavior, or lead to embryonic lethality. ASD patients would have one mutated copy of a gene related to ASD and one normal copy. This research suggests several pathways and development processes that attribute to ASD and could be used to validate ASD mouse models that are used in biomedical research.

“The level of competition in Georgia was at an all-time high this year,” said Georgia Bio President and CEO Maria Thacker. “Georgia Bio is thrilled to have Mokshith represent our state on the international stage at the upcoming BIO Convention, and we are proud to support this Georgia scholar in his future endeavors.”

Georgia Bio also congratulates the Georgia BioGENEius runner-up,  Varun Sendilraj ,who is a senior at Lambert High School in Suwanee, GA. Varun developed a mobile app, DFUCare, which uses deep-learning algorithms to diagnose, analyze and monitor Diabetic Foot Ulcers (DFU) in diabetes patients. DFU is a major complication of diabetes mellitus that can lead to amputation and mortality if left untreated. Caring for DFU can be expensive and time consuming, which limits treatment options for many patients around the globe. DFUCare quantifies the size of wounds, performs tissue analysis, and detects healing potential over time. It can also allow doctors and patients to share medical reports with experts, saving time and resources for treating diabetic foot ulcers.

Judging the 2022 Georgia BioGENEius Challenge were Jamie L. Graham, Boehringer Ingelheim; Ralph L. Cordell, CDC; Ian Biggs, UGA; and Alex Harvey, ViaMune, Inc.

“I am amazed at the quality and thoughtfulness of the projects on display,” said Ian Biggs of UGA’s Innovation Gateway. “The insights displayed, and the obvious effort put into the projects is way beyond my expectations.”

National and International winners will be announced after the competition. See the  International BioGENEius website  for more information on the 2022 schedule. Winners will receive cash scholarships.

Follow the BioGENEius Challenge:  Throughout the challenge, @BiotechInstitut will be tweeting interviews, photos, and engaging with the biotechnology community by using the hashtag #BioGENEius.

About the Biotechnology Institute

The Biotechnology Institute is an independent, national nonprofit organization dedicated to education about the present and future impact of biotechnology. Its mission is to engage, excite and educate the public, particularly students and teachers, about biotechnology and its immense potential for solving human health, food and environmental problems. For more information, visit  www.biotechinstitute.org.

About the BioEd Institute

The BioEd Institute, a division of the 501(c)(3) nonprofit the Center for Global Health Innovation, works to strengthen Georgia’s life sciences workforce pipeline through classroom-to-career initiatives that align with industry needs. BioEd works closely with its sister organization Georgia Bio, which serves the state’s life science industry. For more information about BioEd, visit them online at  www.georgiabioed.org , or on Facebook (@GeorgiaBioEd), Twitter (@georgiabioed), or LinkedIn (@georgia-bioed).

Contacts

Kristin Boscan
585.943.8699
kboscan@cghi.org

By Maria Thacker Goethe April 18, 2025
The Science & Community Impacts Mapping Project (SCIMaP) shows how proposed federal funding cuts lead to reduced economic activity and job losses nationwide.
By Sheran Brown April 10, 2025
Georgia Life Sciences Selects Fulton County Schools Innovation Academy Student as the 2025 Georgia BioGENEius Winner Sandy Springs & Rockmart Teens Take Top Honors in Statewide Science Competition Atlanta, GA (April 4, 2025) – Georgia Life Sciences today named Bhavya Alapati , a junior at Fulton County Schools Innovation Academy, as the winner of the 2025 Georgia BioGENEius Challenge, the premier competition for high school students that recognizes outstanding research and innovation in the biotechnology field. Eleven students from across Georgia competed for this year’s title and cash prize. Bhavya’s project investigated a novel method of identifying strokes using a device she created called SpectroStroke, a small-scale spectrophotometer, to detect homocysteine, an amino acid product that is associated with stroke. Bhavya identified the ability of homocysteine to be detected using Ellman’s reagent, which reacts with the free sulfhydryl group on the molecule to produce a yellow color. Bhavya created a wearable patch that contains the Ellman’s reagent. Then, she designed the SpectroStroke to be able to detect the color change when the patch is exposed to elevated levels of homocysteine. Bhavya’s SpectroStroke can detect normal levels of homocysteine up to extremely high levels seen in those experiencing a stroke. The ability to detect a stroke earlier would reduce damage and long-term effects of the condition. A future iteration of the SpectroStroke would include real-time monitoring capabilities to help track changing homocysteine levels. "Supporting and celebrating outstanding research and innovation in biotechnology is vital for the future of science and medicine. The Georgia BioGENEius Challenge not only encourages the brightest young minds to explore their potential but also nurtures the next generation of leaders who will drive groundbreaking advancements in biotechnology,” said Georgia Life Sciences President and CEO Maria Thacker-Goethe. “By recognizing and empowering these students, we are helping to shape a future where innovation thrives and the possibilities for improving lives are endless. Well done, Bhavya!” Georgia Life Sciences also congratulates the Georgia BioGENEius runner-up, Shelby Kendrick , who is a senior at Paulding County High School in Dallas, GA. Shelby’s research investigated the ability of Aspergillus terreus, a fungus found in soil, to degrade pre-treated polypropylene plastic (PP). This fungus has been discovered to produce high concentrations of degrading enzymes and raises the moisture level of its substrate. Shelby isolated the fungus from soil samples and confirmed the species using PCR amplification and DNA barcoding. Samples of polypropylene were pre-treated with 75% ethanol and UV exposure, then placed in a liquid culture of A. terreus in Minimal Salt Medium (MSM) media, and the culture was incubated for 23 days. At the end of the trial period, PP samples were analyzed using Scanning Electron Microscopy. These samples showed changes in their surface layer, indicating evidence of biodegradation. Polypropylene plastic is found in household items such as plastic cups and is a known problem in the environment due to its inability to degrade. Shelby’s future research on the use of A. terreus for biodegradation includes optimizing degradation conditions and assessing methods of application in the environment. Judging the 2025 Georgia BioGENEius Challenge were Ralph L. Cordell, CDC, and Alex Harvey, ViaMune. Cash prizes were awarded to Bhavya and Shelby. # # # About Georgia Life Sciences Georgia Life Sciences, founded in 1989, is a non-profit, membership-based organization that promotes the interests and growth of the life sciences industry. It is the state’s largest and most influential life sciences advocacy and business leadership organization working to improve access to innovative discoveries that have lifesaving impact. The association connects business, academia, government, and other allied entities involved in the application of life sciences products to fuel growth and collaboration through policy development, community programs, national industry initiatives, and a portfolio of educational and networking events. Learn more at galifesciences.org.
By Maria Thacker Goethe April 9, 2025
Emerging biotechnology is key for U.S. to remain dominant and secure future economic growth in a new era of global competition
MORE POSTS